How COVID Became a More Efficient Virus: Scientists

How COVID Became a More Efficient Virus: Scientists

LA JOLLA, CALIFORNIA — The coronavirus had bifurcated into G and A viruses when COVID-19 spread to California in March, according to new research published in Cell.

The paper's authors state that the G viruses, which are now the dominant type globally, are differentiated from A viruses by variations in the spike protein.

Spike proteins are the sugar-protein structures on the coronavirus's shell that help the pathogen break into host cells.

The G type coronaviruses replicate more efficiently than D viruses by a factor of two or three times.

This means patients infected by the G strain have more viruses in their body.

However, testing samples from six San Diego residents, the scientists found that human antibodies eliminated the G strain as well as, if not better than, the D strain.

In a news release, lead author Erica Saphire of La Jolla Institute says being weaker and less deadly is perhaps the G variant's competitive advantage, as people who are asymptotic or mildly symptomatic are more likely to infect others.