JAMA Network Open is a monthly open access medical journal published by the American Medical Association covering all aspects of the biomedical sciences. It was established in 2018 and the founding editor-in-chief is Fred Rivara. The journal is funded by article processing charges and most articles are available under a Creative Commons license. Article titles and abstracts are translated into Spanish and Chinese. According to Journal Citation Reports, the journal has a 2021 impact factor of 13.353, ranking it 15th out of 172 journals in the category "Medicine, General & Internal". Additionally, it ranks 5th among purely open access journals in that subject category.