Avignon is the prefecture of the Vaucluse department in the Provence-Alpes-Côte d'Azur region of southeastern France. Located on the left bank of the river Rhône, the commune had a population of 93,671 as of the census results of 2017, with about 16,000 living in the ancient town centre enclosed by its medieval walls. It is France's 35th-largest metropolitan area according to INSEE with 337,039 inhabitants (2020), and France's 13th-largest urban unit with 459,533 inhabitants (2020). Its urban area was the fastest-growing in France from 1999 until 2010 with an increase of 76% of its population and an area increase of 136%. The Communauté d'agglomération du Grand Avignon, a cooperation structure of 16 communes, had 197,102 inhabitants in 2022.